Though in guy, cholestyramine resin produces an increase in hepatic synthesis of cholesterol, plasma cholesterol levels fall.

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Chronic usage of cholestyramine resin could possibly be related to increased bleeding tendency as a consequence of hypoprothrombinemia associated with Vitamin K deficiency. This will often respond instantly to parenteral Vitamin K1 and recurrences can be prevented by oral administration of Vitamin K1.

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Other activities (not essentially drug similar) reported in sufferers getting cholestyramine resin contain:

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The relevance of this laboratory observation from research in rats into the clinical use of cholestyramine resin is not recognised. Inside the LRC-CPPT analyze referred to previously mentioned, the entire incidence of deadly and nonfatal neoplasms was similar in the two remedy groups. If the many alternative types of tumors are examined, various alimentary system cancers ended up somewhat far more common while in the cholestyramine group. The small quantities plus the a number of types protect against conclusions from becoming drawn.

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